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http://purl.uniprot.org/citations/12004135http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12004135http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12004135http://www.w3.org/2000/01/rdf-schema#comment"E2F-6 contributes to gene silencing in a manner independent of retinoblastoma protein family members. To better elucidate the molecular mechanism of repression by E2F-6, we have purified the factor from cultured cells. E2F-6 is found in a multimeric protein complex that contains Mga and Max, and thus the complex can bind not only to the E2F-binding site but also to Myc- and Brachyury-binding sites. Moreover, the complex contains chromatin modifiers such as a novel histone methyltransferase that modifies lysine 9 of histone H3, HP1gamma, and Polycomb group (PcG) proteins. The E2F-6 complex preferentially occupies target promoters in G0 cells rather than in G1 cells. These data suggest that these chromatin modifiers contribute to silencing of E2F- and Myc-responsive genes in quiescent cells."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.org/dc/terms/identifier"doi:10.1126/science.1069861"xsd:string
http://purl.uniprot.org/citations/12004135http://purl.org/dc/terms/identifier"doi:10.1126/science.1069861"xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/author"Ishiguro K."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/author"Ishiguro K."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/author"Ogawa H."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/author"Ogawa H."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/author"Nakatani Y."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/author"Nakatani Y."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/author"Livingston D.M."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/author"Livingston D.M."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/author"Gaubatz S."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/author"Gaubatz S."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/pages"1132-1136"xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/pages"1132-1136"xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/title"A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/title"A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells."xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/volume"296"xsd:string
http://purl.uniprot.org/citations/12004135http://purl.uniprot.org/core/volume"296"xsd:string