| http://purl.uniprot.org/citations/12019221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12019221 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12019221 | http://www.w3.org/2000/01/rdf-schema#comment | "A central feature of all adaptive radiations is morphological divergence, but the phenotypic innovations that are responsible are rarely known. When selected in a spatially structured environment, populations of the bacterium Pseudomonas fluorescens rapidly diverge. Among the divergent morphs is a mutant type termed "wrinkly spreader" (WS) that colonizes a new niche through the formation of self-supporting biofilms. Loci contributing to the primary phenotypic innovation were sought by screening a WS transposon library for niche-defective (WS(-)) mutants. Detailed analysis of one group of mutants revealed an operon of 10 genes encoding enzymes necessary to produce a cellulose-like polymer (CLP). WS genotypes overproduce CLP and overproduction of the polymer is necessary for the distinctive morphology of WS colonies; it is also required for biofilm formation and to maximize fitness in spatially structured microcosms, but overproduction of CLP alone is not sufficient to cause WS. A working model predicts that modification of cell cycle control of CLP production is an important determinant of the phenotypic innovation. Analysis of >30 kb of DNA encoding traits required for expression of the WS phenotype, including a regulatory locus, has not revealed the mutational causes, indicating a complex genotype-phenotype map."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/161.1.33"xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/161.1.33"xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/author | "Rainey P.B."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/author | "Rainey P.B."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/author | "Spiers A.J."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/author | "Spiers A.J."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/author | "Bohannon J."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/author | "Bohannon J."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/author | "Kahn S.G."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/author | "Kahn S.G."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/author | "Travisano M."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/author | "Travisano M."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/pages | "33-46"xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/pages | "33-46"xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/title | "Adaptive divergence in experimental populations of Pseudomonas fluorescens. I. Genetic and phenotypic bases of wrinkly spreader fitness."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/title | "Adaptive divergence in experimental populations of Pseudomonas fluorescens. I. Genetic and phenotypic bases of wrinkly spreader fitness."xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/volume | "161"xsd:string |
| http://purl.uniprot.org/citations/12019221 | http://purl.uniprot.org/core/volume | "161"xsd:string |