| http://purl.uniprot.org/citations/12023368 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12023368 | http://www.w3.org/2000/01/rdf-schema#comment | "We describe regulatory effects that a novel neurotrophin-1/B cell-stimulating factor-3 (NNT-1/BSF-3; also reported as cardiotrophin-like cytokine) has on B cell function. NNT-1/BSF-3 stimulates B cell proliferation and Ig production in vitro. NNT-1/BSF-3-transgenic mice, engineered to express NNT-1/BSF-3 in the liver under control of the apolipoprotein E promoter, show B cell hyperplasia with particular expansion of the mature follicular B cell subset in the spleen and the prominent presence of plasma cells. NNT-1/BSF-3-transgenic mice show high serum levels of IgM, IgE, IgG2b, IgG3, anti-dsDNA Abs, and serum amyloid A. NNT-1/BSF-3-transgenic mice also show non-amyloid mesangial deposits that contain IgM, IgG, and C3 and are characterized by a distinctive ultrastructure similar to that of immunotactoid glomerulopathy. NNT-1/BSF-3-transgenic mice produce high amounts of Ag-specific IgM, IgA, and IgE and low amounts of IgG2a and IgG3. Normal mice treated with NNT-1/BSF-3 also produce high amounts of Ag-specific IgE. NNT-1/BSF-3 regulates immunity by stimulating B cell function and Ab production, with preference for Th2 over Th1 Ig types."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.168.11.5690"xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Guo J."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Xu W."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Chang M.S."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Fletcher F.A."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Boone T."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Sarmiento U."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Senaldi G."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Van G."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Cattley R.C."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Stolina M."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "McCabe S."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Faggioni R."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/author | "Kaufman S.A."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/pages | "5690-5698"xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/title | "Regulatory effects of novel neurotrophin-1/b cell-stimulating factor-3 (cardiotrophin-like cytokine) on B cell function."xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://purl.uniprot.org/core/volume | "168"xsd:string |
| http://purl.uniprot.org/citations/12023368 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12023368 |
| http://purl.uniprot.org/citations/12023368 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12023368 |
| http://purl.uniprot.org/uniprot/Q9QZM3#attribution-E2125BF16123F0353EC88BDB62D022F9 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12023368 |
| http://purl.uniprot.org/uniprot/Q9QZM3#attribution-FFC985B16EA82A9E6495368350F78B4F | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12023368 |