| http://purl.uniprot.org/citations/12039559 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12039559 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12039559 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
| http://purl.uniprot.org/citations/12039559 | http://www.w3.org/2000/01/rdf-schema#comment | "The hypoxic response in animals is mediated by hydroxylation of proline residues in the alpha-subunit of hypoxia inducible factor (HIF). Hydroxylation is catalysed by prolyl-4-hydroxylases (PHD isozymes in humans) which are iron(II) and 2-oxoglutarate dependent oxygenases. Mutation of the arginine proposed to bind 2-oxoglutarate and of the 2His-1-carboxylate iron(II) binding motif in PHD1 dramatically reduces its activity. The source of the oxygen of the product alcohol is (>95%) dioxygen."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0960-894x(02)00219-6"xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0960-894x(02)00219-6"xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Oldham N.J."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Oldham N.J."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Horsfall L.E."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Horsfall L.E."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Schofield C.J."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Schofield C.J."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Ratcliffe P.J."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Ratcliffe P.J."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Hewitson K.S."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Hewitson K.S."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "McNeill L.A."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "McNeill L.A."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Maxwell P.H."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Maxwell P.H."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Pugh C.W."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Pugh C.W."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Gleadle J.M."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/author | "Gleadle J.M."xsd:string |
| http://purl.uniprot.org/citations/12039559 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |