http://purl.uniprot.org/citations/12044980 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12044980 | http://www.w3.org/2000/01/rdf-schema#comment | "Cytokine-polarized T cells have distinct chemokine receptor (CKR) expression patterns associated with their cytokine secretion profiles. In order to investigate this paradigm in autoreactive human T cells, we have determined the CKR expression pattern of myelin basic protein (MBP)-reactive T cell lines (TCL) and compared these profiles to those of TCL-generated in response to tetanus toxoid (TT). Expression of CXCR6 and CXCR3 on TCL was significantly positively correlated with IFNgamma, and inversely correlated with IL-5 production. TT TCL had significantly higher expression of CCR7(-)/CD45RA(-) T effector memory (Tem) cells than MBP TCL. However, in MBP-specific TCL, CXCR6 was found to be the best marker of conversion to the Tem phenotype. CXCR6 and CXCR3 are likely to be important in the migration of effector memory T cells in Th1-mediated inflammatory diseases such as multiple sclerosis (MS)."xsd:string |
http://purl.uniprot.org/citations/12044980 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0165-5728(02)00106-6"xsd:string |
http://purl.uniprot.org/citations/12044980 | http://purl.uniprot.org/core/author | "Yun S.H."xsd:string |
http://purl.uniprot.org/citations/12044980 | http://purl.uniprot.org/core/author | "Calabresi P.A."xsd:string |
http://purl.uniprot.org/citations/12044980 | http://purl.uniprot.org/core/author | "Whartenby K.A."xsd:string |
http://purl.uniprot.org/citations/12044980 | http://purl.uniprot.org/core/author | "Allie R."xsd:string |
http://purl.uniprot.org/citations/12044980 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12044980 | http://purl.uniprot.org/core/name | "J Neuroimmunol"xsd:string |
http://purl.uniprot.org/citations/12044980 | http://purl.uniprot.org/core/pages | "96-105"xsd:string |
http://purl.uniprot.org/citations/12044980 | http://purl.uniprot.org/core/title | "Chemokine receptor expression on MBP-reactive T cells: CXCR6 is a marker of IFNgamma-producing effector cells."xsd:string |
http://purl.uniprot.org/citations/12044980 | http://purl.uniprot.org/core/volume | "127"xsd:string |
http://purl.uniprot.org/citations/12044980 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12044980 |
http://purl.uniprot.org/citations/12044980 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12044980 |
http://purl.uniprot.org/uniprot/#_A0N0N3-mappedCitation-12044980 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12044980 |
http://purl.uniprot.org/uniprot/#_O00574-mappedCitation-12044980 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12044980 |
http://purl.uniprot.org/uniprot/A0N0N3 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12044980 |
http://purl.uniprot.org/uniprot/O00574 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12044980 |