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http://purl.uniprot.org/citations/12044980http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12044980http://www.w3.org/2000/01/rdf-schema#comment"Cytokine-polarized T cells have distinct chemokine receptor (CKR) expression patterns associated with their cytokine secretion profiles. In order to investigate this paradigm in autoreactive human T cells, we have determined the CKR expression pattern of myelin basic protein (MBP)-reactive T cell lines (TCL) and compared these profiles to those of TCL-generated in response to tetanus toxoid (TT). Expression of CXCR6 and CXCR3 on TCL was significantly positively correlated with IFNgamma, and inversely correlated with IL-5 production. TT TCL had significantly higher expression of CCR7(-)/CD45RA(-) T effector memory (Tem) cells than MBP TCL. However, in MBP-specific TCL, CXCR6 was found to be the best marker of conversion to the Tem phenotype. CXCR6 and CXCR3 are likely to be important in the migration of effector memory T cells in Th1-mediated inflammatory diseases such as multiple sclerosis (MS)."xsd:string
http://purl.uniprot.org/citations/12044980http://purl.org/dc/terms/identifier"doi:10.1016/s0165-5728(02)00106-6"xsd:string
http://purl.uniprot.org/citations/12044980http://purl.uniprot.org/core/author"Yun S.H."xsd:string
http://purl.uniprot.org/citations/12044980http://purl.uniprot.org/core/author"Calabresi P.A."xsd:string
http://purl.uniprot.org/citations/12044980http://purl.uniprot.org/core/author"Whartenby K.A."xsd:string
http://purl.uniprot.org/citations/12044980http://purl.uniprot.org/core/author"Allie R."xsd:string
http://purl.uniprot.org/citations/12044980http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12044980http://purl.uniprot.org/core/name"J Neuroimmunol"xsd:string
http://purl.uniprot.org/citations/12044980http://purl.uniprot.org/core/pages"96-105"xsd:string
http://purl.uniprot.org/citations/12044980http://purl.uniprot.org/core/title"Chemokine receptor expression on MBP-reactive T cells: CXCR6 is a marker of IFNgamma-producing effector cells."xsd:string
http://purl.uniprot.org/citations/12044980http://purl.uniprot.org/core/volume"127"xsd:string
http://purl.uniprot.org/citations/12044980http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12044980
http://purl.uniprot.org/citations/12044980http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12044980
http://purl.uniprot.org/uniprot/#_A0N0N3-mappedCitation-12044980http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12044980
http://purl.uniprot.org/uniprot/#_O00574-mappedCitation-12044980http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12044980
http://purl.uniprot.org/uniprot/A0N0N3http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/12044980
http://purl.uniprot.org/uniprot/O00574http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/12044980