| http://purl.uniprot.org/citations/12060739 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12060739 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12060739 | http://www.w3.org/2000/01/rdf-schema#comment | "Mammalian tRNA synthetases form a macromolecular complex with three nonenzyme factors: p43, p38, and p18. Here we introduced a mutation within the mouse p38 gene to understand its functional significance for the formation of the multi-tRNA synthetase complex. The complex was completely disintegrated by the deficiency of p38. In addition, the protein levels and catalytic activities of the component enzymes and cofactors were severely decreased. A partial truncation of the p38 polypeptide separated the associated components into different subdomains. The mutant mice showed lethality within 2 days of birth. Thus, this work provides the first evidence, to our knowledge, that p38 is essential for the structural integrity of the multi-tRNA synthetase complex and mouse viability."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.122110199"xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.122110199"xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Kim H.J."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Kim H.J."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Kim S."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Kim S."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Park H."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Park H."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Kim J.Y."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Kim J.Y."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Lee J.-W."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Lee J.-W."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Ahn Y.H."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Ahn Y.H."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Kang Y.-S."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Kang Y.-S."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Ko Y.-G."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/author | "Ko Y.-G."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/12060739 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |