| http://purl.uniprot.org/citations/12070132 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12070132 | http://www.w3.org/2000/01/rdf-schema#comment | "Characterization of mammalian NSF (G274E) and Drosophila NSF (comatose) mutants revealed an evolutionarily conserved NSF activity distinct from ATPase-dependent SNARE disassembly that was essential for Golgi membrane fusion. Analysis of mammalian NSF function during cell-free assembly of Golgi cisternae from mitotic Golgi fragments revealed that NSF disassembles Golgi SNAREs during mitotic Golgi fragmentation. A subsequent ATPase-independent NSF activity restricted to the reassembly phase is essential for membrane fusion. NSF/alpha-SNAP catalyze the binding of GATE-16 to GOS-28, a Golgi v-SNARE, in a manner that requires ATP but not ATP hydrolysis. GATE-16 is essential for NSF-driven Golgi reassembly and precludes GOS-28 from binding to its cognate t-SNARE, syntaxin-5. We suggest that this occurs at the inception of Golgi reassembly to protect the v-SNARE and regulate SNARE function."xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200202082"xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/author | "Sagiv Y."xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/author | "Elazar Z."xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/author | "Newman R."xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/author | "Warren G."xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/author | "Shima D.T."xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/author | "Shorter J."xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/author | "Muller J.M."xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/author | "Deinhardt K."xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/name | "J Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/pages | "1161-1173"xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/title | "Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion."xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://purl.uniprot.org/core/volume | "157"xsd:string |
| http://purl.uniprot.org/citations/12070132 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12070132 |
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