| http://purl.uniprot.org/citations/12072203 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12072203 | http://www.w3.org/2000/01/rdf-schema#comment | "Clear cell sarcoma (CCS), malignant melanoma of soft parts, is a rare malignant tumor with a poor prognosis. In this study, a CCS cell line, designated MP-CCS-SY, was established from a metastatic tumor of a 17-year-old Japanese girl that originated in the left Achilles tendon. A small number of melanosomes were detected in the cytoplasm by electron microscopy. The melanosomes immunoreacted with two melanoma-associated antibodies, HMB45 and Melan-A. A Western blot demonstrated the existence of a Melan-A antigen in this cell line. Although a t(12;22)(q13;q12), which is characteristic of CCS, was not identified by a chromosomal analysis with conventional banding techniques, fluorescence in situ hybridization analysis with painting probes of chromosomes 12 and 22 revealed the insertion of a chromosome 12 fragment into one of the long arms of chromosome 22. The chimeric EWS/ATF1 transcript was detected by the reverse transcriptase polymerase chain reaction. Extra copies and structural abnormalities of chromosome 8 were observed. Overexpression of c-myc mRNA was detected by Northern blot analysis and may have a role in malignant progression of CCS. The availability of this MP-CCS-SY cell line will help to understand the molecular biology of this malignancy and should be useful as a tool for developing an immunotherapy."xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0165-4608(01)00641-0"xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/author | "Kuroda H."xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/author | "Asada Y."xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/author | "Sugimoto T."xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/author | "Maehara Y."xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/author | "Epstein A.L."xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/author | "Moritake H."xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/author | "Yoshida M.A."xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/name | "Cancer Genet Cytogenet"xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/pages | "48-56"xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/title | "Newly established clear cell sarcoma (malignant melanoma of soft parts) cell line expressing melanoma-associated Melan-A antigen and overexpressing C-MYC oncogene."xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://purl.uniprot.org/core/volume | "135"xsd:string |
| http://purl.uniprot.org/citations/12072203 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12072203 |
| http://purl.uniprot.org/citations/12072203 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12072203 |
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| http://purl.uniprot.org/uniprot/#_A0A384MR46-mappedCitation-12072203 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12072203 |
| http://purl.uniprot.org/uniprot/#_B3CJ86-mappedCitation-12072203 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12072203 |
| http://purl.uniprot.org/uniprot/#_B3CJ87-mappedCitation-12072203 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12072203 |
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| http://purl.uniprot.org/uniprot/#_B3CJB3-mappedCitation-12072203 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12072203 |