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http://purl.uniprot.org/citations/12074933 | http://www.w3.org/2000/01/rdf-schema#comment | "The structural similarity between substance P (SP, Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH(2)) and Arg/Pro rich bactericidal peptides suggests a possible direct effect of SP on invasive microbes. We now present evidence that substance P possesses direct antimicrobial activity, highest against S. aureus. A substance P antagonist also possesses such activity but while less potent than substance P agonist S. aureus, is more potent than substance P against C. albicans. Our data also show that the endogenous peptides bradykinin and neurotensin, that also play role in modulation of the host-defense system in situ, have antimicrobial properties but are less potent than substance P."xsd:string |
http://purl.uniprot.org/citations/12074933 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0024-3205(02)01740-x"xsd:string |
http://purl.uniprot.org/citations/12074933 | http://purl.uniprot.org/core/author | "Kowalska K."xsd:string |
http://purl.uniprot.org/citations/12074933 | http://purl.uniprot.org/core/author | "Carr D.B."xsd:string |
http://purl.uniprot.org/citations/12074933 | http://purl.uniprot.org/core/author | "Lipkowski A.W."xsd:string |
http://purl.uniprot.org/citations/12074933 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12074933 | http://purl.uniprot.org/core/name | "Life Sci"xsd:string |
http://purl.uniprot.org/citations/12074933 | http://purl.uniprot.org/core/pages | "747-750"xsd:string |
http://purl.uniprot.org/citations/12074933 | http://purl.uniprot.org/core/title | "Direct antimicrobial properties of substance P."xsd:string |
http://purl.uniprot.org/citations/12074933 | http://purl.uniprot.org/core/volume | "71"xsd:string |
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