| http://purl.uniprot.org/citations/12088418 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12088418 | http://www.w3.org/2000/01/rdf-schema#comment | "Natural killer (NK) cells and interferon-(IFN) gamma have been implicated in immune surveillance against tumor development. Here we show tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), which is a type II membrane protein belonging to the TNF family and plays a critical role in the NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous growth of TRAIL-sensitive tumors. Administration of a neutralizing monoclonal antibody against TRAIL promoted outgrowth of subcutaneously inoculated TRAIL-sensitive tumors (L929, LB27.4, and Renca) but not TRAIL-resistant tumors (P815 and B16). Such a protective effect of TRAIL against TRAIL-sensitive tumors was abrogated in NK cell-depleted or IFN-gamma-deficient mice. These results suggested a substantial role of TRAIL as the effector molecule that eliminates subcutaneously developing TRAIL-sensitive tumors."xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.org/dc/terms/identifier | "doi:10.1006/cimm.2001.1896"xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/author | "Okumura K."xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/author | "Takeda K."xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/author | "Yamaguchi N."xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/author | "Hayakawa Y."xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/author | "Yagita H."xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/author | "Smyth M.J."xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/author | "Cretney E."xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/name | "Cell Immunol"xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/pages | "194-200"xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/title | "Involvement of tumor necrosis factor-related apoptosis-inducing ligand in NK cell-mediated and IFN-gamma-dependent suppression of subcutaneous tumor growth."xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://purl.uniprot.org/core/volume | "214"xsd:string |
| http://purl.uniprot.org/citations/12088418 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12088418 |
| http://purl.uniprot.org/citations/12088418 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12088418 |
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| http://purl.uniprot.org/uniprot/#_A0A7R8C347-mappedCitation-12088418 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12088418 |
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