| http://purl.uniprot.org/citations/12089510 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12089510 | http://www.w3.org/2000/01/rdf-schema#comment | "Fc epsilon RI activation of mast cells is thought to involve Lyn and Syk kinases proximal to the receptor and the signaling complex organized by the linker for activation of T cells (LAT). We report here that Fc epsilon RI also uses a Fyn kinase-dependent pathway that does not require Lyn kinase or the adapter LAT for its initiation, but is necessary for mast cell degranulation. Lyn-deficiency enhanced Fyn-dependent signals and degranulation, but inhibited the calcium response. Fyn-deficiency impaired degranulation, whereas Lyn-mediated signaling and calcium was normal. Thus, Fc epsilon RI-dependent mast cell degranulation involves cross-talk between Fyn and Lyn kinases."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni817"xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/author | "Rivera J."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/author | "Saitoh S."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/author | "Gonzalez-Espinosa C."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/author | "Gadina M."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/author | "O'Shea J.J."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/author | "Samelson L.E."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/author | "Odom S."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/author | "Kovarova M."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/author | "Parravicini V."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/author | "Furumoto Y."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/name | "Nat Immunol"xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/pages | "741-748"xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/title | "Fyn kinase initiates complementary signals required for IgE-dependent mast cell degranulation."xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://purl.uniprot.org/core/volume | "3"xsd:string |
| http://purl.uniprot.org/citations/12089510 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12089510 |
| http://purl.uniprot.org/citations/12089510 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12089510 |
| http://purl.uniprot.org/uniprot/#_A0A0C4DH25-mappedCitation-12089510 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12089510 |
| http://purl.uniprot.org/uniprot/#_A0A0C4DH73-mappedCitation-12089510 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12089510 |
| http://purl.uniprot.org/uniprot/#_A0A075B6P5-mappedCitation-12089510 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12089510 |
| http://purl.uniprot.org/uniprot/#_A0A075B6S6-mappedCitation-12089510 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12089510 |
| http://purl.uniprot.org/uniprot/#_D3YVZ0-mappedCitation-12089510 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12089510 |