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| http://purl.uniprot.org/citations/12095637 | http://www.w3.org/2000/01/rdf-schema#comment | "The physiological function of a recently cloned splice variant of insulin-like growth factor-I (IGF-I; mechano growth factor (MGF)) was studied using an in vitro cell model. Unlike mature IGF-I, the distinct E domain of MGF inhibits terminal differentiation whilst increasing myoblast proliferation. Blocking the IGF-I receptor with a specific antibody indicated that the function of MGF E domain is mediated via a different receptor. The results provide a basis for localized tissue adaptation and helps explain why loss of muscle mass occurs in the elderly and in dystrophic muscle in which MGF production is markedly affected."xsd:string |
| http://purl.uniprot.org/citations/12095637 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(02)02918-6"xsd:string |
| http://purl.uniprot.org/citations/12095637 | http://purl.uniprot.org/core/author | "Yang S.Y."xsd:string |
| http://purl.uniprot.org/citations/12095637 | http://purl.uniprot.org/core/author | "Goldspink G."xsd:string |
| http://purl.uniprot.org/citations/12095637 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12095637 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/12095637 | http://purl.uniprot.org/core/pages | "156-160"xsd:string |
| http://purl.uniprot.org/citations/12095637 | http://purl.uniprot.org/core/title | "Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation."xsd:string |
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