| http://purl.uniprot.org/citations/12097508 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12097508 | http://www.w3.org/2000/01/rdf-schema#comment | "The alpha5 subunit of the GABA(A) receptor is localized mainly to the hippocampus of the mammalian brain. The significance of this rather distinct localization and the function of alpha5-containing GABA(A) receptors has been explored by targeted disruption of the alpha5 gene in mice. The alpha5 -/-mice showed a significantly improved performance in a water maze model of spatial learning, whereas the performance in non-hippocampal-dependent learning and in anxiety tasks were unaltered in comparison with wild-type controls. In the CA1 region of hippocampal brain slices from alpha5 -/-mice, the amplitude of the IPSCs was decreased, and paired-pulse facilitation of field EPSP (fEPSP) amplitudes was enhanced. These data suggest that alpha5-containing GABA(A) receptors play a key role in cognitive processes by controlling a component of synaptic transmission in the CA1 region of the hippocampus."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.org/dc/terms/identifier | "doi:10.1523/jneurosci.22-13-05572.2002"xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Smith A."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Atack J.R."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Whiting P.J."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Rosahl T.W."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "McKernan R.M."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Sur C."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Dawson G.R."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Seabrook G.R."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Jarolimek W."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Howell O."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Collinson N."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Kuenzi F.M."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Cothliff R."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Maubach K.A."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/author | "Otu F.M."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/name | "J Neurosci"xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/pages | "5572-5580"xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/title | "Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the alpha 5 subunit of the GABAA receptor."xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://purl.uniprot.org/core/volume | "22"xsd:string |
| http://purl.uniprot.org/citations/12097508 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12097508 |
| http://purl.uniprot.org/citations/12097508 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12097508 |