| http://purl.uniprot.org/citations/12119358 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12119358 | http://www.w3.org/2000/01/rdf-schema#comment | "p21(Cip1/WAF1) has cell cycle inhibitory activity by binding to and inhibiting both cyclin/Cdk kinases and proliferating cell nuclear antigen. Here we show that p21(Cip1/WAF1) is induced in the cytoplasm during the course of differentiation of chick retinal precursor cells and N1E-115 cells. Ectopic expression of p21(Cip1/WAF1) lacking the nuclear localization signal in N1E-115 cells and NIH3T3 cells affects the formation of actin structures, characteristic of inactivation of Rho. p21(Cip1/WAF1) forms a complex with Rho-kinase and inhibits its activity in vitro and in vivo. Neurite outgrowth and branching from the hippocampal neurons are promoted if p21(Cip1/WAF1) is expressed abundantly in the cytoplasm. These results suggest that cytoplasmic p21(Cip1/WAF1) may contribute to the developmental process of the newborn neurons that extend axons and dendrites into target regions."xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200202071"xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://purl.uniprot.org/core/author | "Tanaka H."xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://purl.uniprot.org/core/author | "Yoshikawa H."xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://purl.uniprot.org/core/author | "Yamashita T."xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://purl.uniprot.org/core/author | "Mizutani S."xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://purl.uniprot.org/core/author | "Tohyama M."xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://purl.uniprot.org/core/author | "Asada M."xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12119358 | http://purl.uniprot.org/core/name | "J Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://purl.uniprot.org/core/pages | "321-329"xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://purl.uniprot.org/core/title | "Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity."xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://purl.uniprot.org/core/volume | "158"xsd:string |
| http://purl.uniprot.org/citations/12119358 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12119358 |
| http://purl.uniprot.org/citations/12119358 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12119358 |
| http://purl.uniprot.org/uniprot/#_P39689-mappedCitation-12119358 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12119358 |
| http://purl.uniprot.org/uniprot/#_Q4FK34-mappedCitation-12119358 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12119358 |
| http://purl.uniprot.org/uniprot/#_Q564P6-mappedCitation-12119358 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12119358 |
| http://purl.uniprot.org/uniprot/P39689 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12119358 |
| http://purl.uniprot.org/uniprot/Q4FK34 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12119358 |
| http://purl.uniprot.org/uniprot/Q564P6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12119358 |