http://purl.uniprot.org/citations/12121274 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12121274 | http://www.w3.org/2000/01/rdf-schema#comment | "We investigated whether HLA-DR2 or -DR12 alleles in 63 Javanese patients with complicated or non-complicated typhoid fever were associated with severity of disease. No association was observed between HLA type and susceptibility to disease. However, in patients we did find a negative association of DR12 (DRB1*12021) with complicated typhoid fever (P = 0.05; OR = 0.3; 95% CI: 0.1-1.0). No effect of DR2 (DRB1*1502) on outcome (P = 0.46; OR = 1.5; 95% CI: 0.5-4.5) was demonstrated. The odds ratio for DR12 remained unchanged after adjusting for DR2. Tumour necrosis factor alpha (TNF-alpha) production capacity in lipopolysaccharide (LPS)-stimulated whole blood culture, as measured by non-equilibrium radioimmunoassay, was significantly lower in complicated than in non-complicated cases (P = 0.02), confirming previous data. No significant correlation of either DR12 (P = 0.47) or DR2 (P = 0.89) was found with TNF-alpha production capacity. Apparently, protection against complications by DR12 is attributable to other mechanisms."xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1365-2370.2002.00318.x"xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/author | "Joosten I."xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/author | "Tijssen H.J."xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/author | "Dharmana E."xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/author | "Dolmans W.M."xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/author | "Van Der Meer J.W."xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/author | "Gasem M.H."xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/author | "Indarwidayati R."xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/author | "Keuter M."xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/name | "Eur J Immunogenet"xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/pages | "297-300"xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/title | "HLA-DRB1*12 is associated with protection against complicated typhoid fever, independent of tumour necrosis factor alpha."xsd:string |
http://purl.uniprot.org/citations/12121274 | http://purl.uniprot.org/core/volume | "29"xsd:string |
http://purl.uniprot.org/citations/12121274 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12121274 |
http://purl.uniprot.org/citations/12121274 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12121274 |
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-12121274 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12121274 |
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http://purl.uniprot.org/uniprot/#_A0A0A0WDZ3-mappedCitation-12121274 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12121274 |
http://purl.uniprot.org/uniprot/#_A0A0E3DD66-mappedCitation-12121274 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12121274 |
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