http://purl.uniprot.org/citations/12121421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12121421 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12121421 | http://www.w3.org/2000/01/rdf-schema#comment | "The endocytic sorting signal on the low-density lipoprotein receptor for clathrin-mediated internalization is the sequence FDNPVY in the receptor's cytosolic tail. We have used a combination of surface plasmon resonance and crosslinking with a photoactivated peptide probe to demonstrate the interaction between FDNPVY-containing peptides and the mu2 chain of purified AP-2 clathrin adaptors (the complexes responsible for plasma membrane sorting). We show that recognition of the FDNPVY signal is mediated by a binding site in the mu2-subunit that is distinct from the site for the more general YppØ sorting signal, another tyrosine-based sequence also recognized by mu2-adaptin. These results suggest the possibility that low-density lipoprotein receptor uptake may be modulated specifically and independently of other proteins in the clathrin pathway."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.org/dc/terms/identifier | "doi:10.1034/j.1600-0854.2002.30808.x"xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.org/dc/terms/identifier | "doi:10.1034/j.1600-0854.2002.30808.x"xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Kirchhausen T."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Kirchhausen T."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Modis Y."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Modis Y."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Boll W."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Boll W."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Brunner C."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Brunner C."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Prehn S."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Prehn S."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Rapoport I."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/author | "Rapoport I."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/name | "Traffic"xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/name | "Traffic"xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/pages | "590-600"xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/pages | "590-600"xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/title | "The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppO sorting signals at distinct sites."xsd:string |
http://purl.uniprot.org/citations/12121421 | http://purl.uniprot.org/core/title | "The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppO sorting signals at distinct sites."xsd:string |