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http://purl.uniprot.org/citations/12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12123607http://www.w3.org/2000/01/rdf-schema#comment"Here we present the identification and characterization of dHb9, the Drosophila homolog of vertebrate Hb9, which encodes a factor central to motorneuron (MN) development. We show that dHb9 regulates neuronal fate by restricting expression of Lim3 and Even-skipped (Eve), two homeodomain (HD) proteins required for development of distinct neuronal classes. Also, dHb9 and Lim3 are activated independently of each other in a virtually identical population of ventrally and laterally projecting MNs. Surprisingly, dHb9 represses Lim3 cell nonautonomously in a subset of dorsally projecting MNs, revealing a novel role for intercellular signaling in the establishment of neuronal fate in Drosophila. Lastly, we provide evidence that dHb9 and Eve regulate each other's expression through Groucho-dependent crossrepression. This mutually antagonistic relationship bears similarity to the crossrepressive relationships between pairs of HD proteins that pattern the vertebrate neural tube."xsd:string
http://purl.uniprot.org/citations/12123607http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(02)00743-2"xsd:string
http://purl.uniprot.org/citations/12123607http://purl.uniprot.org/core/author"Skeath J.B."xsd:string
http://purl.uniprot.org/citations/12123607http://purl.uniprot.org/core/author"Broihier H.T."xsd:string
http://purl.uniprot.org/citations/12123607http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12123607http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/12123607http://purl.uniprot.org/core/pages"39-50"xsd:string
http://purl.uniprot.org/citations/12123607http://purl.uniprot.org/core/title"Drosophila homeodomain protein dHb9 directs neuronal fate via crossrepressive and cell-nonautonomous mechanisms."xsd:string
http://purl.uniprot.org/citations/12123607http://purl.uniprot.org/core/volume"35"xsd:string
http://purl.uniprot.org/citations/12123607http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12123607
http://purl.uniprot.org/citations/12123607http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12123607
http://purl.uniprot.org/uniprot/Q9VSC2#attribution-F0CED211A412DAAE035AC611B4ADD413http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_D2NUE8-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_P14003-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_A8JNN0-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_M9NCY1-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_P10090-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_O96686-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_M9PGF6-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_P34082-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_M9PD53-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_P06602-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_M9PJ19-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607
http://purl.uniprot.org/uniprot/#_P92031-mappedCitation-12123607http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12123607