http://purl.uniprot.org/citations/12127981 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12127981 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12127981 | http://www.w3.org/2000/01/rdf-schema#comment | "Mammalian L-isomer dehydrogenases represent an expansive and well characterized class of metabolic enzymes. Surprisingly, little is known regarding their evolutionarily distinct counterparts, D-isomer dehydrogenases, since few mammalian D-isomer 2-hydroxy acid enzymes have been isolated. Here we present the identification and initial characterization of putative human and murine D-lactate dehydrogenases (DLD) that can interact with the muscle-specific cysteine-rich protein CRP3/MLP. Sequence analysis reveals that the human and mouse transcripts encode novel proteins that display strong similarities to the yeast D-lactate dehydrogenase proteins DLD1, AIP2, and YEL071W. Expression analysis of the mammalian proteins indicates widespread distribution with transcripts present in striated muscle tissues and a variety of other tissue types. Immunofluorescence subcellular localization of the mouse DLD protein indicates that it resides within mitochondria, a feature shared by many dehydrogenases. The identification of the human and mouse DLD clones provides new insight regarding the activity of D-isomer-specific enzymes in mammalian cells."xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0006-291x(02)00768-4"xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0006-291x(02)00768-4"xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/author | "Konieczny S.F."xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/author | "Konieczny S.F."xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/author | "Flick M.J."xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/author | "Flick M.J."xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/pages | "910-916"xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/pages | "910-916"xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/title | "Identification of putative mammalian D-lactate dehydrogenase enzymes."xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/title | "Identification of putative mammalian D-lactate dehydrogenase enzymes."xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/volume | "295"xsd:string |
http://purl.uniprot.org/citations/12127981 | http://purl.uniprot.org/core/volume | "295"xsd:string |
http://purl.uniprot.org/citations/12127981 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12127981 |
http://purl.uniprot.org/citations/12127981 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12127981 |
http://purl.uniprot.org/citations/12127981 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12127981 |
http://purl.uniprot.org/citations/12127981 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12127981 |
http://purl.uniprot.org/uniprot/P50463 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12127981 |
http://purl.uniprot.org/embl-cds/AAM50322.1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12127981 |