RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/12144620http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12144620http://www.w3.org/2000/01/rdf-schema#comment"HLA-A and HLA-B alleles of a population from Kenya, Africa were examined by sequencing exon 2 and exon 3 DNA and typing using a Taxonomy-based Sequence-analysis (TBSA) method. Extensive diversities were observed at both HLA-A and HLA-B loci in this population. Forty-one HLA-A alleles were identified from 159 unrelated individuals. The most frequently observed alleles were A*6802 (11.64%), A*02011/09 (9.75%), A*7401/02 (9.43%), A*3001 (7.86%), A*3002 (7.23%) and A*3601 (6.6%). Forty-nine HLA-B alleles were identified in 161 unrelated individuals, including two novel alleles, B*1567 and B*4426. The most frequently observed HLA-B alleles were B*5301 (9.01%), B*5801 (8.38%), B*4201 (7.76%), B*1503 (7.14%), B*1801 (6.21%), and B*5802 (5.90%). The most frequently observed HLA-A-B haplotypes were A*3601-B*5301 (3.55%) and A*3001-B*4201 (3.19%), followed by A*7401/02-B*5801 (2.84%), A*7401/02-B*5802 (2.84%) and A*02011/09-B*1503 (2.13%). Linkage disequilibrium and chi2 analysis showed the association of these HLA-A-B haplotypes at the antigen level to be significant. The frequencies of HLA-A and HLA-B alleles from the Kenyan population were compared with that of a population from Cameroon. The difference in allele and haplotype frequency distributions partly reflected the different ethnic composition of these two African populations."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.org/dc/terms/identifier"doi:10.1034/j.1399-0039.2002.590503.x"xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Luo M."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Mao X."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Brunham R.C."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Pan S."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Plummer F.A."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Embree J."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Ramdahin S."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Ndinya-Achola J."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Njenga S."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Stuart T."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Cheang M."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/author"Bwayo J.B."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/name"Tissue Antigens"xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/pages"370-380"xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/title"HLA-A and HLA-B in Kenya, Africa: allele frequencies and identification of HLA-B*1567 and HLA-B*4426."xsd:string
http://purl.uniprot.org/citations/12144620http://purl.uniprot.org/core/volume"59"xsd:string
http://purl.uniprot.org/citations/12144620http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12144620
http://purl.uniprot.org/citations/12144620http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12144620
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-12144620http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12144620
http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-12144620http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12144620
http://purl.uniprot.org/uniprot/#_A0A0G2R0N3-mappedCitation-12144620http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12144620