| http://purl.uniprot.org/citations/12163334 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12163334 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12163334 | http://www.w3.org/2000/01/rdf-schema#comment | "Human pigmentation, including eye color, has been associated with skin cancer risk. The P gene is the human homologue to the mouse pink-eye dilution locus and is responsible for oculocutaneous albinism type 2 and other phenotypes that confer eye hypopigmentation. The P gene is located on chromosome 15q11.2-q12, which is also the location of a putative eye pigmentation gene (EYCL3) inferred to exist by linkage analysis. Therefore, the P gene is a strong candidate for determination of human eye color. Using a sample of 629 normally pigmented individuals, we found that individuals were less likely to have blue or gray eyes if they had P gene variants Arg305Trp (P = 0.002), Arg419Gln (P = 0.001), or the combination of both variants (P = 0.003). These results suggest that P gene, in part, determines normal phenotypic variation in human eye color and may therefore represent an inherited biomarker of cutaneous cancer risk."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Guerry D."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Guerry D."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Holmes R."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Holmes R."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Kanetsky P.A."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Kanetsky P.A."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Rebbeck T.R."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Rebbeck T.R."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Elder D.E."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Elder D.E."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Halpern A.C."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Halpern A.C."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Schuchter L.M."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Schuchter L.M."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Walker A.H."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/author | "Walker A.H."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/name | "Cancer Epidemiol. Biomarkers Prev."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/name | "Cancer Epidemiol. Biomarkers Prev."xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/pages | "782-784"xsd:string |
| http://purl.uniprot.org/citations/12163334 | http://purl.uniprot.org/core/pages | "782-784"xsd:string |