| http://purl.uniprot.org/citations/12169658 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12169658 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12169658 | http://www.w3.org/2000/01/rdf-schema#comment | "Mutations in anc-1 (nuclear anchorage defective) disrupt the positioning of nuclei and mitochondria in Caenorhabditis elegans. ANC-1 is shown to consist of mostly coiled regions with a nuclear envelope localization domain (called the KASH domain) and an actin-binding domain; this structure was conserved with the Drosophila protein Msp-300 and the mammalian Syne proteins. Antibodies against ANC-1 localized cytoplasmically and were enriched at the nuclear periphery in an UNC-84-dependent manner. Overexpression of the KASH domain or the actin-binding domain caused a dominant negative anchorage defect. Thus, ANC-1 may connect nuclei to the cytoskeleton by interacting with UNC-84 at the nuclear envelope and with actin in the cytoplasm."xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1075119"xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1075119"xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/author | "Han M."xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/author | "Han M."xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/author | "Starr D.A."xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/author | "Starr D.A."xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/pages | "406-409"xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/pages | "406-409"xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/title | "Role of ANC-1 in tethering nuclei to the actin cytoskeleton."xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/title | "Role of ANC-1 in tethering nuclei to the actin cytoskeleton."xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/volume | "298"xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://purl.uniprot.org/core/volume | "298"xsd:string |
| http://purl.uniprot.org/citations/12169658 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12169658 |
| http://purl.uniprot.org/citations/12169658 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12169658 |
| http://purl.uniprot.org/citations/12169658 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12169658 |
| http://purl.uniprot.org/citations/12169658 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12169658 |
| http://purl.uniprot.org/uniprot/Q9N4M4 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12169658 |
| http://purl.uniprot.org/uniprot/Q6YDA5 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12169658 |