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| http://purl.uniprot.org/citations/12175485 | http://www.w3.org/2000/01/rdf-schema#comment | "Spatially and temporally regulated activity of Branchless/Breathless signaling is essential for trachea development in Drosophila. Early ubiquitous breathless (btl) expression is controlled by binding of Trachealess/Tango heterodimers to the btl minimum enhancer. Branchless/Breathless signaling includes a Sprouty-dependent negative feedback loop. We show that late btl expression is a target of Branchless/Breathless signaling and hence, Branchless/Breathless signaling contains a positive feedback loop, which may guarantee a continuous supply of fresh receptors to membranes of growing tracheal branch cells. Branchless/Breathless signaling activates MAP-kinase, which in turn, activates late btl expression and destabilizes Anterior-open, a repressor for late btl expression. Biochemical and genetic analysis indicated that the minimum btl enhancer includes binding sites of Anterior-open."xsd:string |
| http://purl.uniprot.org/citations/12175485 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0925-4773(02)00042-4"xsd:string |
| http://purl.uniprot.org/citations/12175485 | http://purl.uniprot.org/core/author | "Ohshiro T."xsd:string |
| http://purl.uniprot.org/citations/12175485 | http://purl.uniprot.org/core/author | "Emori Y."xsd:string |
| http://purl.uniprot.org/citations/12175485 | http://purl.uniprot.org/core/author | "Saigo K."xsd:string |
| http://purl.uniprot.org/citations/12175485 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12175485 | http://purl.uniprot.org/core/name | "Mech Dev"xsd:string |
| http://purl.uniprot.org/citations/12175485 | http://purl.uniprot.org/core/pages | "3-11"xsd:string |
| http://purl.uniprot.org/citations/12175485 | http://purl.uniprot.org/core/title | "Ligand-dependent activation of breathless FGF receptor gene in Drosophila developing trachea."xsd:string |
| http://purl.uniprot.org/citations/12175485 | http://purl.uniprot.org/core/volume | "114"xsd:string |
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