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http://purl.uniprot.org/citations/12176931http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12176931http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12176931http://www.w3.org/2000/01/rdf-schema#comment"In a previous proteomic study of the human spliceosome, we identified 42 spliceosome-associated factors, including 19 novel ones. Using enhanced mass spectrometric tools and improved databases, we now report identification of 311 proteins that copurify with splicing complexes assembled on two separate pre-mRNAs. All known essential human splicing factors were found, and 96 novel proteins were identified, of which 55 contain domains directly linking them to functions in splicing/RNA processing. We also detected 20 proteins related to transcription, which indicates a direct connection between this process and splicing. This investigation provides the most detailed inventory of human spliceosome-associated factors to date, and the data indicate a number of interesting links coordinating splicing with other steps in the gene expression pathway."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.org/dc/terms/identifier"doi:10.1101/gr.473902"xsd:string
http://purl.uniprot.org/citations/12176931http://purl.org/dc/terms/identifier"doi:10.1101/gr.473902"xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/author"Mann M."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/author"Mann M."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/author"Rappsilber J."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/author"Rappsilber J."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/author"Lamond A.I."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/author"Lamond A.I."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/author"Ryder U."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/author"Ryder U."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/name"Genome Res."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/name"Genome Res."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/pages"1231-1245"xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/pages"1231-1245"xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/title"Large-scale proteomic analysis of the human spliceosome."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/title"Large-scale proteomic analysis of the human spliceosome."xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/12176931http://purl.uniprot.org/core/volume"12"xsd:string
http://purl.uniprot.org/citations/12176931http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12176931
http://purl.uniprot.org/citations/12176931http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12176931