RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/12194858http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12194858http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12194858http://www.w3.org/2000/01/rdf-schema#comment"Sorting of ubiquitinated endosomal membrane proteins into the MVB pathway is executed by the class E Vps protein complexes ESCRT-I, -II, and -III, and the AAA-type ATPase Vps4. This study characterizes ESCRT-II, a soluble approximately 155 kDa protein complex formed by the class E Vps proteins Vps22, Vps25, and Vps36. This protein complex transiently associates with the endosomal membrane and thereby initiates the formation of ESCRT-III, a membrane-associated protein complex that functions immediately downstream of ESCRT-II during sorting of MVB cargo. ESCRT-II in turn functions downstream of ESCRT-I, a protein complex that binds to ubiquitinated endosomal cargo. We propose that the ESCRT complexes perform a coordinated cascade of events to select and sort MVB cargoes for delivery to the lumen of the vacuole/lysosome."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.org/dc/terms/identifier"doi:10.1016/s1534-5807(02)00219-8"xsd:string
http://purl.uniprot.org/citations/12194858http://purl.org/dc/terms/identifier"doi:10.1016/s1534-5807(02)00219-8"xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/author"Emr S.D."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/author"Emr S.D."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/author"Babst M."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/author"Babst M."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/author"Snyder W.B."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/author"Snyder W.B."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/author"Wendland B."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/author"Wendland B."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/author"Katzmann D.J."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/author"Katzmann D.J."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/name"Dev. Cell"xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/name"Dev. Cell"xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/pages"283-289"xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/pages"283-289"xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/title"Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/title"Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body."xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/volume"3"xsd:string
http://purl.uniprot.org/citations/12194858http://purl.uniprot.org/core/volume"3"xsd:string