| http://purl.uniprot.org/citations/12208516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12208516 | http://www.w3.org/2000/01/rdf-schema#comment | "Plasminogen activator inhibitor-1 (PAI-1) is a key factor of fibrinolytic activity. The activity and mRNA abundance show a daily rhythm. To elucidate the mechanism of daily Pai-1 gene expression, the expression of Pai-1 and several clock genes was examined in the heart of homozygous Clock mutant (Clock/Clock) mice. Damping of the daily oscillation of Pai-1 gene expression in Clock/Clock mice was accompanied with damped or attenuated oscillations of mPer1, mPer2, mBmal1, and mNpas2 mRNA. Daily restricted feeding induced a daily mRNA rhythm of all clock genes and Pai-1 mRNA in Clock/Clock mice as well as wild-type mice. The peaks of clock genes and Pai-1 mRNA were phase-advanced in the heart of both genotypes after 6 days of restricted feeding. The present results demonstrate that daily Pai-1 gene expression depends on clock gene expression in the heart and that a functional Clock gene is not required for restricted feeding-induced resetting of the peripheral clock."xsd:string |
| http://purl.uniprot.org/citations/12208516 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(02)03159-9"xsd:string |
| http://purl.uniprot.org/citations/12208516 | http://purl.uniprot.org/core/author | "Minami Y."xsd:string |
| http://purl.uniprot.org/citations/12208516 | http://purl.uniprot.org/core/author | "Shibata S."xsd:string |
| http://purl.uniprot.org/citations/12208516 | http://purl.uniprot.org/core/author | "Akiyama M."xsd:string |
| http://purl.uniprot.org/citations/12208516 | http://purl.uniprot.org/core/author | "Horikawa K."xsd:string |
| http://purl.uniprot.org/citations/12208516 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12208516 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/12208516 | http://purl.uniprot.org/core/pages | "115-118"xsd:string |
| http://purl.uniprot.org/citations/12208516 | http://purl.uniprot.org/core/title | "Restricted feeding induces daily expression of clock genes and Pai-1 mRNA in the heart of Clock mutant mice."xsd:string |
| http://purl.uniprot.org/citations/12208516 | http://purl.uniprot.org/core/volume | "526"xsd:string |
| http://purl.uniprot.org/citations/12208516 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12208516 |
| http://purl.uniprot.org/citations/12208516 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12208516 |
| http://purl.uniprot.org/uniprot/#_A0A087WQ70-mappedCitation-12208516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12208516 |
| http://purl.uniprot.org/uniprot/#_A0A087WQM1-mappedCitation-12208516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12208516 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YU61-mappedCitation-12208516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12208516 |
| http://purl.uniprot.org/uniprot/#_D0ESZ5-mappedCitation-12208516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12208516 |
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| http://purl.uniprot.org/uniprot/#_Q7TPE9-mappedCitation-12208516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12208516 |
| http://purl.uniprot.org/uniprot/#_P22777-mappedCitation-12208516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12208516 |
| http://purl.uniprot.org/uniprot/#_O08785-mappedCitation-12208516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12208516 |
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| http://purl.uniprot.org/uniprot/#_Q3TWH7-mappedCitation-12208516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12208516 |