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http://purl.uniprot.org/citations/12208521http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12208521http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12208521http://www.w3.org/2000/01/rdf-schema#comment"PIAS3, a member of the protein inhibitor of activated STAT family, was found to interact in vivo and in vitro with TIF2, a previously described coactivator for nuclear receptors. The interaction is mediated by two distinct non-contiguous regions of TIF2. We found that TIF2-PIAS3 interaction occurs through a unique domain of PIAS3, very rich in acidic residues and conserved throughout the PIAS family. PIAS3 modulates the ability of TIF2 to mediate ligand-enhanced transcription activation positively or negatively, for different steroid receptors. Taken together, our results indicate a potential role of PIAS3 as transcriptional modulator of TIF2-mediated signalling."xsd:string
http://purl.uniprot.org/citations/12208521http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(02)03154-x"xsd:string
http://purl.uniprot.org/citations/12208521http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(02)03154-x"xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/author"Gronemeyer H."xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/author"Gronemeyer H."xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/author"Heine M.J.S."xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/author"Heine M.J.S."xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/author"Jimenez-Lara A.M."xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/author"Jimenez-Lara A.M."xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/pages"142-146"xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/pages"142-146"xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/title"PIAS3 (protein inhibitor of activated STAT-3) modulates the transcriptional activation mediated by the nuclear receptor coactivator TIF2."xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/title"PIAS3 (protein inhibitor of activated STAT-3) modulates the transcriptional activation mediated by the nuclear receptor coactivator TIF2."xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/volume"526"xsd:string
http://purl.uniprot.org/citations/12208521http://purl.uniprot.org/core/volume"526"xsd:string
http://purl.uniprot.org/citations/12208521http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12208521
http://purl.uniprot.org/citations/12208521http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12208521
http://purl.uniprot.org/citations/12208521http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12208521
http://purl.uniprot.org/citations/12208521http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12208521