| http://purl.uniprot.org/citations/12215647 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12215647 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12215647 | http://www.w3.org/2000/01/rdf-schema#comment | "Cells have evolved multiple mechanisms to inhibit viral replication. To identify previously unknown antiviral activities, we screened mammalian complementary DNA (cDNA) libraries for genes that prevent infection by a genetically marked retrovirus. Virus-resistant cells were selected from pools of transduced clones, and an active antiviral cDNA was recovered. The gene encodes a CCCH-type zinc finger protein designated ZAP. Expression of the gene caused a profound and specific loss of viral messenger RNAs (mRNAs) from the cytoplasm without affecting the levels of nuclear mRNAs. The finding suggests the existence of a previously unknown machinery for the inhibition of virus replication, targeting a step in viral gene expression."xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1074276"xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1074276"xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/author | "Guo X."xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/author | "Guo X."xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/author | "Gao G."xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/author | "Gao G."xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/author | "Goff S.P."xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/author | "Goff S.P."xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/pages | "1703-1706"xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/pages | "1703-1706"xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/title | "Inhibition of retroviral RNA production by ZAP, a CCCH-type zinc finger protein."xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/title | "Inhibition of retroviral RNA production by ZAP, a CCCH-type zinc finger protein."xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/volume | "297"xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://purl.uniprot.org/core/volume | "297"xsd:string |
| http://purl.uniprot.org/citations/12215647 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12215647 |
| http://purl.uniprot.org/citations/12215647 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12215647 |
| http://purl.uniprot.org/citations/12215647 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12215647 |
| http://purl.uniprot.org/citations/12215647 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12215647 |