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http://purl.uniprot.org/citations/12220497http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12220497http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12220497http://www.w3.org/2000/01/rdf-schema#comment"Desulfovibrio gigas formate dehydrogenase is the first representative of a tungsten-containing enzyme from a mesophile that has been structurally characterized. It is a heterodimer of 110 and 24 kDa subunits. The large subunit, homologous to E. coli FDH-H and to D. desulfuricans nitrate reductase, harbors the W site and one [4Fe-4S] center. No small subunit ortholog containing three [4Fe-4S] clusters has been reported. The structural homology with E. coli FDH-H shows that the essential residues (SeCys158, His159, and Arg407) at the active site are conserved. The active site is accessible via a positively charged tunnel, while product release may be facilitated, for H(+) by buried waters and protonable amino acids and for CO(2) through a hydrophobic channel."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.org/dc/terms/identifier"doi:10.1016/s0969-2126(02)00826-2"xsd:string
http://purl.uniprot.org/citations/12220497http://purl.org/dc/terms/identifier"doi:10.1016/s0969-2126(02)00826-2"xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Huber R."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Huber R."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Moura I."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Moura I."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Moura J.J.G."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Moura J.J.G."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Romao M.J."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Romao M.J."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Teixeira S."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Teixeira S."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Bursakov S."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Bursakov S."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Dias J.M."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Dias J.M."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Macieira S.I.M.G."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Macieira S.I.M.G."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Raaijmakers H."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/author"Raaijmakers H."xsd:string
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12220497http://purl.uniprot.org/core/date"2002"xsd:gYear