| http://purl.uniprot.org/citations/12242347 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12242347 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12242347 | http://www.w3.org/2000/01/rdf-schema#comment | "The GTPase TC10 plays a critical role in insulin-stimulated glucose transport. We report here the identification of the TC10-interacting protein CIP4/2 (Cdc42-interacting protein 4/2) as an effector in this pathway. CIP4/2 localizes to an intracellular compartment under basal conditions and translocates to the plasma membrane on insulin stimulation. Overexpression of constitutively active TC10 brings CIP4/2 to the plasma membrane, whereas overexpression of an inhibitory form of TC10 blocks the translocation of CIP4/2 produced by insulin. Overexpression of mutant forms of CIP4/2 containing an N-terminal deletion or with diminished TC10 binding inhibits insulin-stimulated Glut4 translocation. These data suggest that CIP4/2 may play an important role in insulin-stimulated glucose transport as a downstream effector of TC10."xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.202495599"xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.202495599"xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/author | "Chang L."xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/author | "Chang L."xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/author | "Saltiel A.R."xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/author | "Saltiel A.R."xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/author | "Adams R.D."xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/author | "Adams R.D."xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/pages | "12835-12840"xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/pages | "12835-12840"xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/title | "The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes."xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/title | "The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes."xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/volume | "99"xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://purl.uniprot.org/core/volume | "99"xsd:string |
| http://purl.uniprot.org/citations/12242347 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12242347 |
| http://purl.uniprot.org/citations/12242347 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12242347 |
| http://purl.uniprot.org/citations/12242347 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12242347 |
| http://purl.uniprot.org/citations/12242347 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12242347 |