| http://purl.uniprot.org/citations/12351419 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12351419 | http://www.w3.org/2000/01/rdf-schema#comment | "Tumor necrosis factor (TNF) production and non-Hodgkin lymphoma (NHL) outcome was found to be related to the TNF(-308) polymorphism. To explore whether this could be linked to neighboring polymorphisms, we genotyped the TNF(-376,-308,-238,-163), lymphotoxin alpha (LTalpha)(+252), and HLA DRB1 alleles in 204 patients with NHL and 120 controls. TNF(-308A) was the only allele associated with higher TNF and its p55 and p75 receptors' levels (P =.009, P =.03, and P =.007) and lower complete remission rates (P =.006). Freedom from progression (FFP) and overall survival (OS) were shorter in patients with TNF(-308A) (P =.009 and P =.02), null HLA DRB1*02 allele (P =.007 and P =.14), or both genetic markers (P =.004 and P =.005). Multivariate analysis incorporating International Prognostic Index (IPI) identified TNF(-308A) (P <.0001, relative risk [RR] = 1.63; P <.0001, RR = 1.51) and null HLA DRB1*02 alleles (P =.015, RR = 1.18; P <.0001, RR = 1.25) as independent factors for FFP and OS. These results indicate the existence of at least 2 inherited factors involved in NHL outcome."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.org/dc/terms/identifier | "doi:10.1182/blood-2002-02-0654"xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Kowalski M."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Salles G."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Borowiec M."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Robak T."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Juszczynski P."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Bienvenu J."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Coiffier B."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Warzocha K."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Baseggio L."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Woszczek G."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Kalinka E."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/author | "Lech-Maranda E."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/name | "Blood"xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/pages | "3037-3040"xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/title | "Human leukocyte antigens class II and tumor necrosis factor genetic polymorphisms are independent predictors of non-Hodgkin lymphoma outcome."xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://purl.uniprot.org/core/volume | "100"xsd:string |
| http://purl.uniprot.org/citations/12351419 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12351419 |
| http://purl.uniprot.org/citations/12351419 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12351419 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-12351419 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12351419 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-12351419 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12351419 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-12351419 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12351419 |