http://purl.uniprot.org/citations/12354388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12354388 | http://www.w3.org/2000/01/rdf-schema#comment | "CD4+CD3-cells are the predominant hematopoietic cells found in mouse fetal intestine. We prove their role as Peyer's patch (PP)-inducing cells by transfer into neonatal PP-deficient mice. To test the requirement of chemokines and adhesion molecules in induction of PP, we studied mice deficient in CXCR5 and/or alpha4beta1 integrin-mediated adhesion. CXCR5-/- mice have CD4+CD3-cells, which are inefficient in inducing PP formation. We show here that CXCR5/CXCL13 signaling activates alpha4beta1 integrin on CD4+CD3-cells. Blocking of beta1 integrin or VCAM-1, the ligand of alpha4beta1 integrin, inhibits PP formation. This study demonstrates the link between chemokine receptors and adhesion molecules that regulates stromal/hematopoietic cell interaction leading to PP formation."xsd:string |
http://purl.uniprot.org/citations/12354388 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(02)00395-3"xsd:string |
http://purl.uniprot.org/citations/12354388 | http://purl.uniprot.org/core/author | "Lipp M."xsd:string |
http://purl.uniprot.org/citations/12354388 | http://purl.uniprot.org/core/author | "Acha-Orbea H."xsd:string |
http://purl.uniprot.org/citations/12354388 | http://purl.uniprot.org/core/author | "Finke D."xsd:string |
http://purl.uniprot.org/citations/12354388 | http://purl.uniprot.org/core/author | "Kraehenbuhl J."xsd:string |
http://purl.uniprot.org/citations/12354388 | http://purl.uniprot.org/core/author | "Mattis A."xsd:string |
http://purl.uniprot.org/citations/12354388 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12354388 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
http://purl.uniprot.org/citations/12354388 | http://purl.uniprot.org/core/pages | "363-373"xsd:string |
http://purl.uniprot.org/citations/12354388 | http://purl.uniprot.org/core/title | "CD4+CD3- cells induce Peyer's patch development: role of alpha4beta1 integrin activation by CXCR5."xsd:string |
http://purl.uniprot.org/citations/12354388 | http://purl.uniprot.org/core/volume | "17"xsd:string |
http://purl.uniprot.org/citations/12354388 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12354388 |
http://purl.uniprot.org/citations/12354388 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12354388 |
http://purl.uniprot.org/uniprot/#_A0A0A0MQJ3-mappedCitation-12354388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12354388 |
http://purl.uniprot.org/uniprot/#_A0A1L1SRC9-mappedCitation-12354388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12354388 |
http://purl.uniprot.org/uniprot/#_A0A0G2JFP9-mappedCitation-12354388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12354388 |
http://purl.uniprot.org/uniprot/#_A0A0U5JAA2-mappedCitation-12354388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12354388 |
http://purl.uniprot.org/uniprot/#_A4FUI4-mappedCitation-12354388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12354388 |
http://purl.uniprot.org/uniprot/#_D6RJL5-mappedCitation-12354388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12354388 |
http://purl.uniprot.org/uniprot/#_G3V002-mappedCitation-12354388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12354388 |
http://purl.uniprot.org/uniprot/#_P09055-mappedCitation-12354388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12354388 |
http://purl.uniprot.org/uniprot/#_P29533-mappedCitation-12354388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12354388 |
http://purl.uniprot.org/uniprot/#_Q3U0V9-mappedCitation-12354388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12354388 |