| http://purl.uniprot.org/citations/12356581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12356581 | http://www.w3.org/2000/01/rdf-schema#comment | "To better define the roles of CD11b, CD11a, and one of their endothelial cell receptors, intercellular adhesion molecule-1 (ICAM-1), in the lower respiratory tract inflammatory response to inhaled lipopolysaccharide (LPS), we evaluated the physiologic and biologic response to inhaled LPS in mice receiving anti-CD11b antibody, anti-CD11a antibody, and anti-ICAM-1 antibody. Mice receiving anti-CD11b antibody had a dramatic reduction in pulmonary neutrophil recruitment compared with control mice (18,300 versus 143,000 cells/ml, and neutrophils 16.7% versus 77%), whereas mice receiving anti-CD11a antibody did not demonstrate a reduction in lavage cellularity. Mice receiving anti-ICAM-1 antibody also demonstrated a dose-dependent reduction in inflammatory cell recruitment to the alveolar space. Despite the significant reduction in inflammatory cell infiltrate in mice receiving either CD11b or ICAM-1 antibodies, there was no reduction in the development of airway hyperreactivity. These findings suggest that CD11b and ICAM-1 are important mediators of LPS-induced airway inflammation, but do not appear to be critical to the development of LPS-induced airway hyperreactivity."xsd:string |
| http://purl.uniprot.org/citations/12356581 | http://purl.org/dc/terms/identifier | "doi:10.1165/rcmb.4694"xsd:string |
| http://purl.uniprot.org/citations/12356581 | http://purl.uniprot.org/core/author | "Schwartz D.A."xsd:string |
| http://purl.uniprot.org/citations/12356581 | http://purl.uniprot.org/core/author | "Fuhrman R.M."xsd:string |
| http://purl.uniprot.org/citations/12356581 | http://purl.uniprot.org/core/author | "Moreland J.G."xsd:string |
| http://purl.uniprot.org/citations/12356581 | http://purl.uniprot.org/core/author | "Pruessner J.A."xsd:string |
| http://purl.uniprot.org/citations/12356581 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12356581 | http://purl.uniprot.org/core/name | "Am J Respir Cell Mol Biol"xsd:string |
| http://purl.uniprot.org/citations/12356581 | http://purl.uniprot.org/core/pages | "474-480"xsd:string |
| http://purl.uniprot.org/citations/12356581 | http://purl.uniprot.org/core/title | "CD11b and intercellular adhesion molecule-1 are involved in pulmonary neutrophil recruitment in lipopolysaccharide-induced airway disease."xsd:string |
| http://purl.uniprot.org/citations/12356581 | http://purl.uniprot.org/core/volume | "27"xsd:string |
| http://purl.uniprot.org/citations/12356581 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12356581 |
| http://purl.uniprot.org/citations/12356581 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12356581 |
| http://purl.uniprot.org/uniprot/#_E9Q604-mappedCitation-12356581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12356581 |
| http://purl.uniprot.org/uniprot/#_A1E2I0-mappedCitation-12356581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12356581 |
| http://purl.uniprot.org/uniprot/#_G5E8F1-mappedCitation-12356581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12356581 |
| http://purl.uniprot.org/uniprot/#_P13597-mappedCitation-12356581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12356581 |
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| http://purl.uniprot.org/uniprot/#_Q922B3-mappedCitation-12356581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12356581 |
| http://purl.uniprot.org/uniprot/#_Q3UDJ5-mappedCitation-12356581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12356581 |
| http://purl.uniprot.org/uniprot/#_Q3UE52-mappedCitation-12356581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12356581 |
| http://purl.uniprot.org/uniprot/#_Q3UJ88-mappedCitation-12356581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12356581 |
| http://purl.uniprot.org/uniprot/#_P05555-mappedCitation-12356581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12356581 |