http://purl.uniprot.org/citations/12359369 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12359369 | http://www.w3.org/2000/01/rdf-schema#comment | "In B-cell chronic lymphocytic leukemia (CLL) a high Bcl-2/Bax ratio contributes to death defiance. We sought to identify any genetic changes in the BAX as a possible mechanism for its altered expression in CLL. The BAX gene from the RL cell line and B-cells from 34 CLL patients and 25 controls were sequenced. A novel heterozygous G(-248)A polymorphism in the 5'-UTR was present in 69% of stage I-IV patients and 5.5% of stage 0 patients, and in 4.0% of controls. It was associated with reduced protein expression (P=0.049), progression beyond Rai stage 0 (P=0.00018) and failure to achieve complete response (P=0.038)."xsd:string |
http://purl.uniprot.org/citations/12359369 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0304-3835(02)00378-6"xsd:string |
http://purl.uniprot.org/citations/12359369 | http://purl.uniprot.org/core/author | "Saxena A."xsd:string |
http://purl.uniprot.org/citations/12359369 | http://purl.uniprot.org/core/author | "Viswanathan S."xsd:string |
http://purl.uniprot.org/citations/12359369 | http://purl.uniprot.org/core/author | "Sankaran K."xsd:string |
http://purl.uniprot.org/citations/12359369 | http://purl.uniprot.org/core/author | "Moshynska O."xsd:string |
http://purl.uniprot.org/citations/12359369 | http://purl.uniprot.org/core/author | "Sheridan D.P."xsd:string |
http://purl.uniprot.org/citations/12359369 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12359369 | http://purl.uniprot.org/core/name | "Cancer Lett"xsd:string |
http://purl.uniprot.org/citations/12359369 | http://purl.uniprot.org/core/pages | "199-205"xsd:string |
http://purl.uniprot.org/citations/12359369 | http://purl.uniprot.org/core/title | "Association of a novel single nucleotide polymorphism, G(-248)A, in the 5'-UTR of BAX gene in chronic lymphocytic leukemia with disease progression and treatment resistance."xsd:string |
http://purl.uniprot.org/citations/12359369 | http://purl.uniprot.org/core/volume | "187"xsd:string |
http://purl.uniprot.org/citations/12359369 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12359369 |
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http://purl.uniprot.org/uniprot/#_A0A0C4MW46-mappedCitation-12359369 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12359369 |
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http://purl.uniprot.org/uniprot/#_Q07812-mappedCitation-12359369 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12359369 |
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http://purl.uniprot.org/uniprot/#_I6LPK7-mappedCitation-12359369 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12359369 |
http://purl.uniprot.org/uniprot/#_K4JQN1-mappedCitation-12359369 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12359369 |
http://purl.uniprot.org/uniprot/#_O95074-mappedCitation-12359369 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12359369 |
http://purl.uniprot.org/uniprot/#_Q8WXU1-mappedCitation-12359369 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12359369 |