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http://purl.uniprot.org/citations/12370427http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12370427http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12370427http://www.w3.org/2000/01/rdf-schema#comment"The 3' Ig heavy chain locus (Igh) regulatory region is the most downstream known element of the murine Igh gene cluster. We report here that the nearest non-Igh genes-Crip, Crp2, and Mta1-are located approximately 70 kb further downstream and are beyond the end of the domain of Igh transcriptional regulation. We have localized an origin of replication in MEL cells to a 3-kb segment located between the 3' Igh regulatory region and Crip. Sequences downstream of this origin are replicated by forks that move in both directions. Sequences upstream of this origin (Igh-C, -D, and -J) are replicated in a single direction through a 500-kb segment in which no active bidirectional origins can be detected. We propose that this origin may lie at or near the end of the Igh regulation domain."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.org/dc/terms/identifier"doi:10.1073/pnas.212392399"xsd:string
http://purl.uniprot.org/citations/12370427http://purl.org/dc/terms/identifier"doi:10.1073/pnas.212392399"xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Matsuda F."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Matsuda F."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Zhou J."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Zhou J."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Delepine M."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Delepine M."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Ashouian N."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Ashouian N."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Birshtein B.K."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Birshtein B.K."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Chevillard C."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Chevillard C."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Riblet R."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Riblet R."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Schildkraut C.L."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/author"Schildkraut C.L."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/12370427http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string