| http://purl.uniprot.org/citations/12377117 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12377117 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12377117 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
| http://purl.uniprot.org/citations/12377117 | http://www.w3.org/2000/01/rdf-schema#comment | "In Escherichia coli, RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. The crystal structure of this 2'O-methyltransferase has been determined at 2.5 A resolution. RlmB consists of an N-terminal domain connected by a flexible extended linker to a catalytic C-terminal domain and forms a dimer in solution. The C-terminal domain displays a divergent methyltransferase fold with a unique knotted region, and lacks the classic AdoMet binding site features. The N-terminal domain is similar to ribosomal proteins L7 and L30, suggesting a role in 23S rRNA recognition. The conserved residues in this novel family of 2'O-methyltransferases cluster in the knotted region, suggesting the location of the catalytic and AdoMet binding sites."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0969-2126(02)00852-3"xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0969-2126(02)00852-3"xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Cygler M."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Cygler M."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Michel G."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Michel G."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Matte A."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Matte A."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Larocque R."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Larocque R."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Sauve V."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/author | "Sauve V."xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/name | "Structure"xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/name | "Structure"xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/pages | "1303-1315"xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/pages | "1303-1315"xsd:string |
| http://purl.uniprot.org/citations/12377117 | http://purl.uniprot.org/core/title | "The structure of the RlmB 23S rRNA methyltransferase reveals a new methyltransferase fold with a unique knot."xsd:string |