| http://purl.uniprot.org/citations/12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12391023 | http://www.w3.org/2000/01/rdf-schema#comment | "The number of circulating follicular B lymphocytes is normally kept within a precise range despite their dispersion through the body and daily overproduction of precursors in the bone marrow. By establishing a genome wide recessive mutation screen in C57BL/6 mice to identify critical components of immune system regulation, we identified a mutant strain with selective deficiency in recirculating B cells but not immature or peritoneal B1 cells. Analysis of mixed bone marrow chimeras established that the mutation affects a cell autonomous process within B cells that is required for their accumulation after emigrating to peripheral lymphoid organs. The defect is caused by a point mutation in the gene encoding transcription factor nuclear factor (NF)-kappaB2, terminating the encoded protein within the DNA-binding domain. These findings establish the feasibility of analyzing immune regulation by genome wide mutant screens and demonstrates an intrinsic requirement for NF-kappaB2 in regulating circulating follicular B cell numbers."xsd:string |
| http://purl.uniprot.org/citations/12391023 | http://purl.org/dc/terms/identifier | "doi:10.1084/jem.20020959"xsd:string |
| http://purl.uniprot.org/citations/12391023 | http://purl.uniprot.org/core/author | "Goodnow C.C."xsd:string |
| http://purl.uniprot.org/citations/12391023 | http://purl.uniprot.org/core/author | "Miosge L.A."xsd:string |
| http://purl.uniprot.org/citations/12391023 | http://purl.uniprot.org/core/author | "Blasioli J."xsd:string |
| http://purl.uniprot.org/citations/12391023 | http://purl.uniprot.org/core/author | "Blery M."xsd:string |
| http://purl.uniprot.org/citations/12391023 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12391023 | http://purl.uniprot.org/core/name | "J Exp Med"xsd:string |
| http://purl.uniprot.org/citations/12391023 | http://purl.uniprot.org/core/pages | "1113-1119"xsd:string |
| http://purl.uniprot.org/citations/12391023 | http://purl.uniprot.org/core/title | "Analysis of an ethylnitrosourea-generated mouse mutation defines a cell intrinsic role of nuclear factor kappaB2 in regulating circulating B cell numbers."xsd:string |
| http://purl.uniprot.org/citations/12391023 | http://purl.uniprot.org/core/volume | "196"xsd:string |
| http://purl.uniprot.org/citations/12391023 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12391023 |
| http://purl.uniprot.org/citations/12391023 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12391023 |
| http://purl.uniprot.org/uniprot/#_A0A494B9Y5-mappedCitation-12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12391023 |
| http://purl.uniprot.org/uniprot/#_A0A494BAQ2-mappedCitation-12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12391023 |
| http://purl.uniprot.org/uniprot/#_E9Q418-mappedCitation-12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12391023 |
| http://purl.uniprot.org/uniprot/#_Q64729-mappedCitation-12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12391023 |
| http://purl.uniprot.org/uniprot/#_Q3UV15-mappedCitation-12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12391023 |
| http://purl.uniprot.org/uniprot/#_Q4U105-mappedCitation-12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12391023 |
| http://purl.uniprot.org/uniprot/#_Q4U106-mappedCitation-12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12391023 |
| http://purl.uniprot.org/uniprot/#_Q4U108-mappedCitation-12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12391023 |
| http://purl.uniprot.org/uniprot/#_Q3UG25-mappedCitation-12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12391023 |
| http://purl.uniprot.org/uniprot/#_Q4FJL1-mappedCitation-12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12391023 |
| http://purl.uniprot.org/uniprot/#_Q3U485-mappedCitation-12391023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12391023 |