| http://purl.uniprot.org/citations/12391027 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12391027 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12391027 | http://www.w3.org/2000/01/rdf-schema#comment | "Thrombospondin-1 (TSP-1) contains three type 1 repeats (TSRs), which mediate cell attachment, glycosaminoglycan binding, inhibition of angiogenesis, activation of TGFbeta, and inhibition of matrix metalloproteinases. The crystal structure of the TSRs reported in this article reveals a novel, antiparallel, three-stranded fold that consists of alternating stacked layers of tryptophan and arginine residues from respective strands, capped by disulfide bonds on each end. The front face of the TSR contains a right-handed spiral, positively charged groove that might be the "recognition" face, mediating interactions with various ligands. This is the first high-resolution crystal structure of a TSR domain that provides a prototypic architecture for structural and functional exploration of the diverse members of the TSR superfamily."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200206062"xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200206062"xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Dong Y."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Dong Y."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Joachimiak A."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Joachimiak A."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Liu J.-H."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Liu J.-H."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Tan K."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Tan K."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Zhang R."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Zhang R."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Lawler J."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Lawler J."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Wang J.-H."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Wang J.-H."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Duquette M."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/author | "Duquette M."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/12391027 | http://purl.uniprot.org/core/name | "J. Cell Biol."xsd:string |