| http://purl.uniprot.org/citations/12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12392614 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectiveTo analyze the association between alleles of HLA-DRB1 and type I autoimmune hepatitis (AIH) in patients from Shanghai, China.MethodsIn 32 Chinese patients with type I AIH and 48 healthy controls in Shanghai area, polymerase chain reaction amplification with sequence-specific primers (PCR-SSP) was performed to examine the association of the alleles of HLA-DRB1 and its subtypes with type I AIH.ResultsHLA-DRB1 typing by PCR-SSP showed that DR4 had a significantly increased frequency among patients with AIH versus healthy control (46.9% versus 20.8%; relative risk=3.35, chi(2)=5.99, P=0.014). No other alleles differed significantly between the two groups. In subtypes of DRB1*04, there was a trend for an increase in gene frequency of DRB1*0405 increased in patients with type I AIH versus healthy controls (21.9% vs 6.3%, chi(2)=4.23, P=0.04, but Pc=0.08). The frequency of arginine at position HLA-DR beta 71 of third hypervariable region significantly increased among patients with AIH versus healthy control (46.9% versus 18.8%, chi(2)=7.14, P=0.008).ConclusionsType I AIH in Chinese patients of Shanghai area is associated with HLA-DR4 and arginine at position DR beta 71 of third hypervariable region"xsd:string |
| http://purl.uniprot.org/citations/12392614 | http://purl.uniprot.org/core/author | "Ma X."xsd:string |
| http://purl.uniprot.org/citations/12392614 | http://purl.uniprot.org/core/author | "Qiu D."xsd:string |
| http://purl.uniprot.org/citations/12392614 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12392614 | http://purl.uniprot.org/core/name | "Zhonghua Gan Zang Bing Za Zhi"xsd:string |
| http://purl.uniprot.org/citations/12392614 | http://purl.uniprot.org/core/pages | "347-349"xsd:string |
| http://purl.uniprot.org/citations/12392614 | http://purl.uniprot.org/core/title | "[Relationship between type I autoimmune hepatitis and alleles of HLA-DRB1 in Chinese patients of Shanghai area]."xsd:string |
| http://purl.uniprot.org/citations/12392614 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/12392614 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12392614 |
| http://purl.uniprot.org/citations/12392614 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A0A0WDZ3-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DD66-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A141AZI1-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A141AZI3-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A141AZI4-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A0A0WAE5-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A0A0WB88-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C4B0-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A0A8R917-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_D6CJC2-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3D8-mappedCitation-12392614 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12392614 |