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http://purl.uniprot.org/citations/12393735http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12393735http://www.w3.org/2000/01/rdf-schema#comment"B-lineage-committed cells are believed to arise in the liver of mouse embryos at 14 days after coitus (dpc). However, pre-B-specific gene transcripts and DJH gene rearrangements have been detected in earlier, midgestation embryos. We describe here a population of c-kit(+)AA4.1(+)CD19(+)Pax5(+) cells present in the aorta-gonad-mesonephros (AGM) area and in the livers of 11-dpc mouse embryos. In contrast to multipotent c-kit(+)AA4.1(+)CD19(-) hematopoietic stem cells (HSCs), these c-kit(+)AA4.1(+)CD19(+) progenitors differentiated only to B-lineage cells in vitro. We propose that mouse embryonic B lymphopoiesis starts earlier than previously thought, at 10 to 11 dpc, both in liver and extra-liver hematopoietic sites. The B-cell differentiation program is not delayed with respect to the emerging lymphohematopoiesis events in the midgestation mouse embryo (8-9 dpc)."xsd:string
http://purl.uniprot.org/citations/12393735http://purl.org/dc/terms/identifier"doi:10.1182/blood-2002-03-0809"xsd:string
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/author"Gaspar M.L."xsd:string
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/author"Gonzalo P."xsd:string
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/author"de Andres B."xsd:string
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/author"Marcos M.A."xsd:string
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/author"Minguet S."xsd:string
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/author"Martinez-Marin J.A."xsd:string
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/author"Soro P.G."xsd:string
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/name"Blood"xsd:string
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/pages"4074-4081"xsd:string
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/title"The first 3 days of B-cell development in the mouse embryo."xsd:string
http://purl.uniprot.org/citations/12393735http://purl.uniprot.org/core/volume"100"xsd:string
http://purl.uniprot.org/citations/12393735http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12393735
http://purl.uniprot.org/citations/12393735http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12393735
http://purl.uniprot.org/uniprot/#_A0A0X1KG58-mappedCitation-12393735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12393735
http://purl.uniprot.org/uniprot/#_B7ZMX3-mappedCitation-12393735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12393735
http://purl.uniprot.org/uniprot/#_P13372-mappedCitation-12393735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12393735
http://purl.uniprot.org/uniprot/#_P13373-mappedCitation-12393735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12393735
http://purl.uniprot.org/uniprot/#_Q3U1A5-mappedCitation-12393735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12393735
http://purl.uniprot.org/uniprot/#_P25918-mappedCitation-12393735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12393735
http://purl.uniprot.org/uniprot/#_Q8CD87-mappedCitation-12393735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12393735
http://purl.uniprot.org/uniprot/#_P21784-mappedCitation-12393735http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/12393735