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http://purl.uniprot.org/citations/12397177http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12397177http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12397177http://www.w3.org/2000/01/rdf-schema#comment"Myocardin is a SAP (SAF-A/B, Acinus, PIAS) domain transcription factor that associates with serum response factor (SRF) to potently enhance SRF-dependent transcription. Here we describe two myocardin-related transcription factors (MRTFs), A and B, that also interact with SRF and stimulate its transcriptional activity. Whereas myocardin is expressed specifically in cardiac and smooth muscle cells, MRTF-A and -B are expressed in numerous embryonic and adult tissues. In SRF-deficient embryonic stem cells, myocardin and MRTFs are unable to activate SRF-dependent reporter genes, confirming their dependence on SRF. Myocardin and MRTFs comprise a previously uncharacterized family of SRF cofactors with the potential to modulate SRF target genes in a wide range of tissues."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.org/dc/terms/identifier"doi:10.1073/pnas.222561499"xsd:string
http://purl.uniprot.org/citations/12397177http://purl.org/dc/terms/identifier"doi:10.1073/pnas.222561499"xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Li S."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Li S."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Wang Z."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Wang Z."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Sutherland L."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Sutherland L."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Nordheim A."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Nordheim A."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Olson E.N."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Olson E.N."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Richardson J.A."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Richardson J.A."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Hockemeyer D."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Hockemeyer D."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Wang D.Z."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Wang D.-Z."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Wang D.-Z."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Schratt G."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/author"Schratt G."xsd:string
http://purl.uniprot.org/citations/12397177http://purl.uniprot.org/core/date"2002"xsd:gYear