| http://purl.uniprot.org/citations/12406186 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12406186 | http://www.w3.org/2000/01/rdf-schema#comment | "Alpha-synuclein was originally identified as the presynaptic nerve terminal protein. Recently, we reported that alpha-synuclein is also expressed in cultured human astrocytes and that its levels are increased by stimulation with interleukin-1beta, suggesting that it may be involved in inflammatory processes. We therefore investigated the effect of inflammatory stimuli on alpha-synuclein expression in human macrophages. Alpha-synuclein mRNA and protein were detected in cultured human macrophages and levels of alpha-synuclein protein were increased by stimulation with lipopolysaccharide and interleukin-1beta in a time- and concentration-dependent manner. Immunofluorescent staining showed that alpha-synuclein protein was expressed within the cytoplasm and nucleus. Furthermore, alpha-synuclein immunoreactivity was present in alveolar macrophages from human lung tissues. These findings suggest that the function of alpha-synuclein is not exclusive to the nervous system and that alpha-synuclein may play a role in inflammatory processes and immune responses."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1440-1827.2002.01385.x"xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Satoh K."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Takahashi H."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Sasaki M."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Yoshida H."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Yoshimoto M."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Imaizumi T."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Wakabayashi K."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Tanji K."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Matsumiya T."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Odagiri H."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Mori F."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/author | "Tamo W."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/name | "Pathol Int"xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/pages | "572-577"xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/title | "Upregulation of alpha-synuclein by lipopolysaccharide and interleukin-1 in human macrophages."xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://purl.uniprot.org/core/volume | "52"xsd:string |
| http://purl.uniprot.org/citations/12406186 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12406186 |
| http://purl.uniprot.org/citations/12406186 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12406186 |
| http://purl.uniprot.org/uniprot/P37840#attribution-13D714D42FF2239C6969A31556C587E3 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12406186 |