http://purl.uniprot.org/citations/12419225 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12419225 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12419225 | http://www.w3.org/2000/01/rdf-schema#comment | "Adenosine deaminases that act on RNA (ADARs) are RNA-editing enzymes that deaminate adenosines to create inosines in double-stranded RNA (dsRNA). Here we demonstrate that ADARs are not required for RNA interference (RNAi) and that they do not antagonize the pathway to a detectable level when RNAi is initiated by injecting dsRNA. We find, however, that transgenes expressed in the somatic tissues of wild-type animals are silenced in strains with deletions in the two genes encoding ADARs, adr-1 and adr-2. Transgene-induced gene silencing in adr-1;adr-2 mutants depends on genes required for RNAi, suggesting that a dsRNA intermediate is involved. In wild-type animals we detect edited dsRNA corresponding to transgenes, and we propose that editing of this dsRNA prevents somatic transgenes from initiating RNAi in wild-type animals."xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(02)00649-4"xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(02)00649-4"xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/author | "Bass B.L."xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/author | "Bass B.L."xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/author | "Knight S.W."xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/author | "Knight S.W."xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/pages | "809-817"xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/pages | "809-817"xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/title | "The role of RNA editing by ADARs in RNAi."xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/title | "The role of RNA editing by ADARs in RNAi."xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/volume | "10"xsd:string |
http://purl.uniprot.org/citations/12419225 | http://purl.uniprot.org/core/volume | "10"xsd:string |
http://purl.uniprot.org/citations/12419225 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12419225 |
http://purl.uniprot.org/citations/12419225 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12419225 |
http://purl.uniprot.org/citations/12419225 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12419225 |
http://purl.uniprot.org/citations/12419225 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12419225 |
http://purl.uniprot.org/uniprot/Q9U3D6 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12419225 |
http://purl.uniprot.org/uniprot/Q22618 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/12419225 |