| http://purl.uniprot.org/citations/12422060 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12422060 | http://www.w3.org/2000/01/rdf-schema#comment | "Genetic polymorphism of the serotonin 5-HT(2A) receptor seems to be associated with therapeutic response to selective serotonin reuptake inhibitors (SSRIs). The present study investigated whether a novel -1438G/A polymorphism in the promoter region of the 5-HT(2A )receptor gene is associated with therapeutic response to fluvoxamine (an SSRI) in 66 Japanese patients with major depressive disorder. Fluvoxamine (50 to 200 mg) was administered twice daily for 6 weeks. Fifty-four patients completed this study. The genotype distribution and the allele frequencies showed no significant difference between responders and non-responders. The time-course of the Montgomery-Asberg Depression Rating Scale scores showed no significant difference among -1438G/G, -1438G/A, and -1438A/A genotype groups. The results demonstrated that the -1438G/A promoter polymorphism in the 5-HT(2A) receptor gene was unlikely to have a major role in therapeutic response to fluvoxamine in Japanese patients with major depressive disorder."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.org/dc/terms/identifier | "doi:10.1159/000066394"xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Inoue K."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Itoh K."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Ito K."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Suzuki T."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Sato K."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Shimizu T."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Takahashi H."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Sugawara K."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Yoshida K."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Kamata M."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Ohkubo T."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Tezuka T."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Higuchi H."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/author | "Otani K."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/name | "Neuropsychobiology"xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/pages | "136-140"xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/title | "Association between -1438G/A promoter polymorphism in the 5-HT(2A) receptor gene and fluvoxamine response in Japanese patients with major depressive disorder."xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://purl.uniprot.org/core/volume | "46"xsd:string |
| http://purl.uniprot.org/citations/12422060 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12422060 |
| http://purl.uniprot.org/citations/12422060 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12422060 |
| http://purl.uniprot.org/uniprot/#_B2R7Y7-mappedCitation-12422060 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12422060 |