| http://purl.uniprot.org/citations/12429831 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12429831 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12429831 | http://www.w3.org/2000/01/rdf-schema#comment | "StmF mutants are chemotactic mutants that are defective in a cGMP phosphodiesterase (PDE) activity. We identified a novel gene, PdeD, that harbors two cyclic nucleotide-binding domains and a metallo-beta-lactamase homology domain. Similar to stmF mutants, pdeD-null mutants displayed extensively streaming aggregates, prolonged elevation of cGMP levels after chemotactic stimulation, and reduced cGMP-PDE activity. PdeD transcripts were lacking in stmF mutant NP377, indicating that this mutant carries a PdeD lesion. Expression of a PdeD-YFP fusion protein in pdeD-null cells restored the normal cGMP response and showed that PdeD resides in the cytosol. When purified by immunoprecipitation, the PdeD-YFP fusion protein displayed cGMP-PDE activity, which was retained in a truncated construct that contained only the metallo-beta-lactamase domain."xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e02-05-0285"xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e02-05-0285"xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/author | "Schaap P."xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/author | "Schaap P."xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/author | "Meima M.E."xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/author | "Meima M.E."xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/author | "Biondi R.M."xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/author | "Biondi R.M."xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/pages | "3870-3877"xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/pages | "3870-3877"xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/title | "Identification of a novel type of cGMP phosphodiesterase that is defective in the chemotactic stmF mutants."xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/title | "Identification of a novel type of cGMP phosphodiesterase that is defective in the chemotactic stmF mutants."xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/12429831 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12429831 |
| http://purl.uniprot.org/citations/12429831 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12429831 |
| http://purl.uniprot.org/citations/12429831 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12429831 |
| http://purl.uniprot.org/citations/12429831 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12429831 |