http://purl.uniprot.org/citations/12434334 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12434334 | http://www.w3.org/2000/01/rdf-schema#comment | "Many kinases are required for progression through the eukaryotic cell cycle. The Aurora kinases comprise a highly conserved family of serine/threonine kinases that have been implicated in chromosome segregation and cytokinesis in several organisms. We have isolated a sterile Caenorhabditis elegans mutant in which the majority of the locus encoding the Aurora A kinase air-1 has been deleted. Complementation tests with previously isolated sterile mutations in the air-1 genetic interval demonstrate that the air-1 and let-412 loci are identical. Previous analysis of AIR-1 function by RNA-mediated interference (RNAi) has shown that AIR-1 is required for embryonic survival. The characterization of the three sterile air-1 mutant alleles described here extends these studies by revealing an allelic series that differentially affects postembryonic cell divisions and germline development."xsd:string |
http://purl.uniprot.org/citations/12434334 | http://purl.org/dc/terms/identifier | "doi:10.1002/gene.10157"xsd:string |
http://purl.uniprot.org/citations/12434334 | http://purl.uniprot.org/core/author | "Baillie D.L."xsd:string |
http://purl.uniprot.org/citations/12434334 | http://purl.uniprot.org/core/author | "Furuta T."xsd:string |
http://purl.uniprot.org/citations/12434334 | http://purl.uniprot.org/core/author | "Schumacher J.M."xsd:string |
http://purl.uniprot.org/citations/12434334 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12434334 | http://purl.uniprot.org/core/name | "Genesis"xsd:string |
http://purl.uniprot.org/citations/12434334 | http://purl.uniprot.org/core/pages | "244-250"xsd:string |
http://purl.uniprot.org/citations/12434334 | http://purl.uniprot.org/core/title | "Caenorhabditis elegans Aurora A kinase AIR-1 is required for postembryonic cell divisions and germline development."xsd:string |
http://purl.uniprot.org/citations/12434334 | http://purl.uniprot.org/core/volume | "34"xsd:string |
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