| http://purl.uniprot.org/citations/12444081 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12444081 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12444081 | http://www.w3.org/2000/01/rdf-schema#comment | "Genetic and molecular data have implicated the Drosophila gene female-lethal (2)d (fl (2)d) in alternative splicing regulation of genes involved in sexual determination. Sex-specific splicing is under the control of the female-specific regulatory protein sex-lethal (SXL). Co-immunoprecipitation and mass spectrometry results indicate that SXL and FL (2)D form a complex and that the protein VIRILIZER and a Ran-binding protein implicated in protein nuclear import are also present in complexes containing FL (2)D. A human homolog of FL (2)D was identified and cloned. Interestingly, this gene encodes a protein (WTAP) that was previously found to interact with the Wilms' tumor suppressor-1 (WT1), an isoform of which binds to and co-localizes with splicing factors. Alternative splicing of transformer pre-mRNA, a target of SXL regulation, was affected by immunodepletion of hFL (2)D/WTAP from HeLa nuclear extracts, thus arguing for a biochemical function of FL (2)D/WTAP proteins in splicing regulation."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m210737200"xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m210737200"xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Ortega A."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Ortega A."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Wilm M."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Wilm M."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Sanchez L."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Sanchez L."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Bachi A."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Bachi A."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Niksic M."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Niksic M."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Valcarcel J."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Valcarcel J."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Hastie N."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/author | "Hastie N."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/pages | "3040-3047"xsd:string |
| http://purl.uniprot.org/citations/12444081 | http://purl.uniprot.org/core/pages | "3040-3047"xsd:string |