| http://purl.uniprot.org/citations/12444163 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12444163 | http://www.w3.org/2000/01/rdf-schema#comment | "Type I IFNs (IFN-alpha/beta) modulate innate immune responses. Here we show activation of transcription factor IFN regulatory factor 3, the synthesis of large amounts of IFN-beta mRNA, and type I IFN signal transduction in macrophages infected with Listeria monocytogenes. Expression of the bacterial virulence protein listeriolysin O was necessary, but not sufficient, for efficient IFN-beta production. Signaling through a pathway involving the type I IFN receptor and Stat1 sensitized macrophages to L. monocytogenes-induced cell death in a manner not requiring inducible NO synthase (nitric oxide synthase 2) or protein kinase R, potential effectors of type I IFN action during microbial infections. The data stress the importance of type I IFN for the course of infections with intracellular bacteria and suggest that factors other than listeriolysin O contribute to macrophage death during Listeria infection."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.169.11.6522"xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/author | "Chakraborty T."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/author | "Muller M."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/author | "Decker T."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/author | "Levy D.E."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/author | "Unger H."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/author | "Steinborn R."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/author | "Stockinger S."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/author | "Kolbe T."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/author | "Stoiber D."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/author | "Bayr L."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/author | "Materna T."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/pages | "6522-6529"xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/title | "Production of type I IFN sensitizes macrophages to cell death induced by Listeria monocytogenes."xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://purl.uniprot.org/core/volume | "169"xsd:string |
| http://purl.uniprot.org/citations/12444163 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12444163 |
| http://purl.uniprot.org/citations/12444163 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12444163 |
| http://purl.uniprot.org/uniprot/#_A0A087WSP5-mappedCitation-12444163 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12444163 |
| http://purl.uniprot.org/uniprot/#_A0A087WSQ5-mappedCitation-12444163 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12444163 |
| http://purl.uniprot.org/uniprot/#_A0A1L1STZ4-mappedCitation-12444163 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12444163 |
| http://purl.uniprot.org/uniprot/#_A0A087WRI1-mappedCitation-12444163 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12444163 |