| http://purl.uniprot.org/citations/12445820 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12445820 | http://www.w3.org/2000/01/rdf-schema#comment | "The ZntR protein from Escherichia coli is a member of the MerR-family of transcriptional regulatory proteins and acts as a hyper-sensitive transcriptional switch primarily in response to Zn(II) and Cd(II). The binding of metal-ions to ZntR initiates a mechanism that remodels the cognate promoter, increasing its affinity for RNA polymerase. We have introduced site-directed mutations into zntR and shown that cysteine and histidine residues are important for transcriptional control and have an effect on metal-ion preference, sensitivity and magnitude of induction. We propose a three-dimensional model of the N-terminal region of ZntR based upon the coordinates of the MerR-family regulator BmrR."xsd:string |
| http://purl.uniprot.org/citations/12445820 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0006-291x(02)02660-8"xsd:string |
| http://purl.uniprot.org/citations/12445820 | http://purl.uniprot.org/core/author | "Khan S."xsd:string |
| http://purl.uniprot.org/citations/12445820 | http://purl.uniprot.org/core/author | "Jones G.W."xsd:string |
| http://purl.uniprot.org/citations/12445820 | http://purl.uniprot.org/core/author | "Morby A.P."xsd:string |
| http://purl.uniprot.org/citations/12445820 | http://purl.uniprot.org/core/author | "Brocklehurst K.R."xsd:string |
| http://purl.uniprot.org/citations/12445820 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12445820 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/12445820 | http://purl.uniprot.org/core/pages | "438-445"xsd:string |
| http://purl.uniprot.org/citations/12445820 | http://purl.uniprot.org/core/title | "The functional analysis of directed amino-acid alterations in ZntR from Escherichia coli."xsd:string |
| http://purl.uniprot.org/citations/12445820 | http://purl.uniprot.org/core/volume | "299"xsd:string |
| http://purl.uniprot.org/citations/12445820 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12445820 |
| http://purl.uniprot.org/citations/12445820 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12445820 |
| http://purl.uniprot.org/uniprot/#_P0ACS5-mappedCitation-12445820 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12445820 |
| http://purl.uniprot.org/uniprot/P0ACS5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12445820 |