| http://purl.uniprot.org/citations/12453641 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12453641 | http://www.w3.org/2000/01/rdf-schema#comment | "Our previous studies indicated that cell surface proteoglycans were mostly heparan sulfate ones (HSPG) in 20 day-old Sertoli cells [Biochim. Biophys. Acta 1510 (2001) 474]. Among these HSPG, glypican-1, syndecans-1 and -4 mRNAs were expressed and differentially regulated. Glypican-1 and syndecan-1 mRNA expression was up-regulated under PKC activation in contrast to syndecan-4 mRNA expression which was not affected [Biochim. Biophys. Acta 1474 (2000) 31]. Rat Sertoli cells undergo extensive changes during the postnatal period both in structure and function, as the hematotesticular barrier establishment occurs at around 20 day-old. The testicular PKCalpha expression in developing Sertoli cells results in (i) a soluble (inactive) form which is maximal at the age of 1 day and declines gradually thereafter and (ii) a particulate (active) form which is low at birth, increases six-fold on days 8-11 of age and declines thereafter. The present study focused on the glypican-1, syndecan-1 and syndecan-4 mRNA expression and regulation under PKC activation by the phorbol myristate acetate (PMA) in 10-30 day-old Sertoli cells. Our data indicated that the regulation of their expression specifically depends on the nature of HSPG and Sertoli cell developmental stage and evidenced a specific PKC regulation of HSPG mRNA expression."xsd:string |
| http://purl.uniprot.org/citations/12453641 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0300-9084(02)01430-x"xsd:string |
| http://purl.uniprot.org/citations/12453641 | http://purl.uniprot.org/core/author | "Villers C."xsd:string |
| http://purl.uniprot.org/citations/12453641 | http://purl.uniprot.org/core/author | "Brucato S."xsd:string |
| http://purl.uniprot.org/citations/12453641 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12453641 | http://purl.uniprot.org/core/name | "Biochimie"xsd:string |
| http://purl.uniprot.org/citations/12453641 | http://purl.uniprot.org/core/pages | "681-686"xsd:string |
| http://purl.uniprot.org/citations/12453641 | http://purl.uniprot.org/core/title | "Protein kinase C regulation of glypican-1, syndecan-1 and syndecan-4 mRNAs expression during rat Sertoli cell development."xsd:string |
| http://purl.uniprot.org/citations/12453641 | http://purl.uniprot.org/core/volume | "84"xsd:string |
| http://purl.uniprot.org/citations/12453641 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12453641 |
| http://purl.uniprot.org/citations/12453641 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12453641 |
| http://purl.uniprot.org/uniprot/P26260#attribution-70F6F63949718ACA615985C67CB92A53 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/12453641 |
| http://purl.uniprot.org/uniprot/#_P26260-mappedCitation-12453641 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/12453641 |
| http://purl.uniprot.org/uniprot/P26260 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/12453641 |