| http://purl.uniprot.org/citations/12454284 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12454284 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12454284 | http://www.w3.org/2000/01/rdf-schema#comment | "HLA-G is a nonclassical class I MHC molecule with an unknown function and with unusual characteristics that distinguish it from other class I MHC molecules. Here, we demonstrate that HLA-G forms disulfide-linked dimers that are present on the cell surface. Immunoprecipitation of HLA-G from surface biotinylated transfectants using the anti-beta2-microglobulin mAb BBM.1 revealed the presence of an approximately equal 78-kDa form of HLA-G heavy chain that was reduced by using DTT to a 39-kDa form. Mutation of Cys-42 to a serine completely abrogated dimerization of HLA-G, suggesting that the disulfide linkage formed exclusively through this residue. A possible interaction between the HLA-G monomer or dimer and the KIR2DL4 receptor was also investigated, but no interaction between these molecules could be detected through several approaches. The cell-surface expression of dimerized HLA-G molecules may have implications for HLA-Greceptor interactions and for the search for specific receptors that bind HLA-G."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.212643199"xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.212643199"xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Strominger J.L."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Strominger J.L."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Whitman M.C."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Whitman M.C."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Angelisova P."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Angelisova P."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Horejsi V."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Horejsi V."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Erskine R."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Erskine R."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Boyson J.E."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Boyson J.E."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Chiu M."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Chiu M."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Koopman L.A."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Koopman L.A."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Lau J.M."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Lau J.M."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Valter M.M."xsd:string |
| http://purl.uniprot.org/citations/12454284 | http://purl.uniprot.org/core/author | "Valter M.M."xsd:string |